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MECLONAZEPAM

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What is Meclonazepam?

Synonyms : 3S)-5-(2-chlorophenyl)-3-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one

CAS No. : 58662-84-3

Molecular Formula : C16H12ClN3O3

Molecular Weight : 329.74

Product description :
Meclonazepam ((S)-3-methylclonazepam) is a drug which is a benzodiazepine derivative similar in structure to clonazepam. It has sedative and anxiolytic actions like those of other benzodiazepines,and also has anti-parasitic effects against the parasitic worm Schistosoma mansoni.

Your Introduction to Meclonazepam

  it is basically benzodiazepine which was first found in 1970`s. it was discovered in a Swiss health company which believed it was cure for anxiety disorders. However, with passage of time they realized it was never listed as medicine which means it can be sold without a hitch in EU. it has the IUPAC name of 3S-5-2 Chlorophenyl-3-methyl-7-nitro1 and it is believed to have a half-life as compared to other benzos which are available in the market. This is an analogue of Clonazepam and it is expected to reach in an orderly fashion in lab observation.

It was basically discovered by the team of Hoffman La Roche. It is identified as a Sedative as it has anxiolytic actions which can be compared to other benzodiazepines. In addition, it also has anti parasitic effects against the parasitic worms.

ABSTRACT DETAIL

The new analogues of it are prepared and evaluated right against schistosoma mansoni. According to biological data, the substitution at position of it can never provide promising analogue for prophylactic and therapeutic activity.

GRAPHICAL ABSTRACT

According to this, there are healthy chances that the it can provide some promising analogues for prophylactic and therapeutic activity.

MODERNIZATION

In 2012, the first designer Benzodiazepines hit internet market shelves as the alternative to prescription only benzodiazepines. Not long after, these compounds were scheduled for different countries. The new substance such as clonazolam stated to hit the scene as well. These compounds were found with the help of nuclear magnetic resonance spectroscopy with electro ionization mass quadruple time of flight mass.

The major in microsomes are identified for flubromazolam. Meclonazepam also signals at mass to charge ratio corresponding to reduction of nitro group to anime. Moreover, no metabolites are formed by combination of reduction and mono dihydroxylation as these were detected. This information will help to analyse such drugs as biological samples.

SAFETY CONCERNS

Alcohol

Alcohol ingestion with it can be the cause of CNS effects. The two substance potentiate each other very well and can be unpredictable in some cases.  These can lead to unconsciousness with some vomit aspiration if the subject is not placed in care. Worst case scenario also includes backing out and even memory loss

GBL

The two substance will potentiate each other and thus these can lead to unconsciousness as well. Leading to the same outcome of vomit aspiration which is a risk if not given proper care

Opioids

The central nervous system, if respiratory are providing these can be additively and synergistically present. The two substance can also potential each other strong and unpredictably.

Tramadol

The central nervous system can be additively and synergistically present. The vomit aspiration is a risk if the subject has passed away or not provided with proper medical care.

Both these substance potential ataxia and sedation can be caused by other and leads to unexpected loss of consciousness at high dose. Meanwhile the small dose of Benzo can also take you to a bad trip but it won’t be as bad as messing with it.

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